Parkinson’s disease is a chronic and progressive neurodegenerative disorder of the central nervous system which involves the loss of the dopaminergic neurones in the substantia nigra region of the brain and affects millions of people worldwide. This part of the brain is rich in dopaminergic neurons. Dopamine is a chemical neurotransmitter that is responsible for the transmission of signals from one part of the brain to another. It thereby helps in the muscular control and coordination of the body. Loss of the dopaminergic neurons lead to the deficiency of dopamine and hence various motor symptoms of the Parkinson’s disease manifest, which continue and worsen over time. There is no definitive line of diagnosis or management for the Parkinson’s disease. The diagnosis is usually based on the neurological clinical examination conducted by a knowledgeable and experienced [… Read More]
Parkinson’s disease is a chronic progressive neurodegenerative disorder of the central nervous system caused due to the dying dopaminergic neurons in the nigro-striatal region of the brain. It is a disease of gradual onset, sometimes starting with a barely noticeable tremor in just one hand. The disease often goes undetected for a long time as the motor symptoms like tremors, rigidity, stiffness, slowing of movements, hunched over back takes years to develop. The clinical diagnosis is based on the neurological examination conducted by experienced and knowledgeable neurophysician. However, once the diagnosis is made, it paves way to the start of a difficult journey leading to a myriad of new challenges for the disabled as well as their family. Parkinson’s disease usually affects the individuals in their golden years of relaxation. However, the disability must not [… Read More]
Parkinson disease is a chronically progressive neurodegenerative disorder of the central nervous system which is gradual in onset and is characterized by the loss of dopaminergic neurons in the nigrostriatal region of the brain. Dopamine is a chemical messenger or neurotransmitter which is responsible for carrying the signals from one part of the brain to another and usually controls the muscular movement and coordination. The deficiency of dopamine leads to the symptoms of movement disorder, like tremors, rigidity, stiffness, slowing of the movements, frequent falls and freezing of the gait which continues and worsens over time. The diagnosis of Parkinson’s disease is purely clinical and is based on the neurological examination. There is no specific line of management for this neurodegenerative disease. In addition to the medicinal therapeutic agents, various alternative approaches have been employed [… Read More]
The chronic progressive neurodegenerative Parkinson’s disease occurs due to the damage to the dopaminergic neurones in the nigro-striatal region of the brain. Dopaminergic neurons are responsible for the production of neurotransmitter Dopamine, which is predominantly involved in the muscular control and coordination of the body, deficiency of which results in the manifestation of various movement disorder symptoms like tremors, rigidity, stiffness, slowing of movements, frequent falls and freezing of gait. Various therapeutic medications, surgical treatments, homeopathy, stem cell culture, gene therapy, mind energy and body energy techniques have been employed in the treatment of Parkinson’s disease. However, there is no specific line of management of the disease, the best possible outcome arises from the synergistic effect of various combinations of the above mentioned techniques, which are advised on the case individual basis. One such technique [… Read More]
Parkinson’s disease the chronic neurodegenerative disorder with progressive is caused due to the deficiency of chemical neurotransmitter dopamine. This dopamine deficiency is the result of insult or injury to the nigrostriatal region of the brain. People with Parkinson’s experience a myriad of premotor and motor symptoms including tremors, stiffness, rigidity, slowness of movements, frequent falls and freezing of gait Due to the absence of any specific disease modifying cure, the mainstay of the therapeutic treatment against Parkinson’s disease lies in the dopamine replacement. Parkinson’s patients may also seek relief from their symptoms using various types of complementary medicines. Scientists all over the world have done various researches which have lead to the evolution of our understanding towards the Parkinson’s disease in terms of both diagnosis as well as treatment. These therapies support or complement the [… Read More]
Parkinson’s disease, Alzheimer’s disease and multiple sclerosis are degenerative neurological conditions where the patient may suffer from progressive loss of normal motor functioning, mental changes, and a gradual but relentless course leading to loss of cognitive abilities. Despite some similar signs and symptoms, these conditions, however, are different in many ways and in their presentation. At times, there is confusion among people who are not familiar with these conditions. Parkinson’s Disease (PD) Parkinson’s disease is a neurodegenerative disorder where there is degeneration of the cells of a part of the brain known as the substantia nigra, resulting in dopamine deficiency. Dopamine is a chemical transmitter which is involved in transmitting signals within the brain that help to coordinate movements. Loss of dopamine produces problems with movement and coordination that is the characteristic of PD. PD [… Read More]
Parkinson’s disease is the second most common chronic progressive neurodegenerative disorder, which comes to play as a result of the neurotransmitter dopamine deficiency caused due to an insult to the dopamine producing neurons, predominantly located in the nigrostriatal region of the brain. The dopamine, which is chiefly responsible to transport the chemical signals, control the muscular control and coordination, and hence its deficiency manifests as a constellation of motor function impairment symptoms. The disease process is grossly incapacitating. Ranging from constipation, sleep disturbances to tremors, rigidity and eventually the loss of complete control over the muscle coordination, alongside the severe psychotic and behavioral disturbances, causes extreme depression in the Parkinson’s patients. The utter embarrassment due to loss of independence and self esteem, in adjunct to the compulsive behavioral disturbances push the patients in the pitfall [… Read More]
Parkinson’s disease can be very demanding on the caregivers, especially in the end stages of Parkinson’s disease, when the patient is wheelchair bound or absolutely bedridden. This is the time when extra precautions have to be taken to prevent bedsore formation. Bedsores (also called pressure sores or decubitus ulcers) can be extremely painful and usually develop as a result of prolonged immobilization. It is better to take precautions to prevent bedsore formation because once they develop they can progress very fast and then become extremely difficult to heal.
Due to the progressive loss of muscle control – both voluntary and involuntary – many other symptoms can develop in a patient suffering from Parkinson’s disease besides the typical symptoms of tremor and rigidity. Dysphagia is one such symptom. Dysphagia or difficulty in swallowing is a common problem in people with Parkinson’s disease which can have far-reaching consequences. Dysphagia can lead to shorter survival time in a patient with Parkinson’s disease, not only because the affected muscles of the throat may make swallowing difficult – hence less food intake and increased chances of under-nutrition of the patient – but also because it increases the possibility of aspiration pneumonia.
Since Parkinson’s disease management depends mainly on oral medication, patient compliance or patient adherence to the medicines prescribed as well as not quitting the drugs altogether without informing the doctor is a very important issue. The absolute necessity of taking the medicines at proper times and in their prescribed doses cannot be overemphasized and should be clearly understood by the patient, family members or other caregivers. The dangers of quitting Parkinson’s disease drugs without informing the doctor also needs to be stressed.